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High-quality Etomidate API supplied by Macroline Health Care — a trusted exporter of Pharmaceutical APIs and Advance Intermediates with regulatory grade and documentation support.
Macroline Health Care supplies Etomidate API for pharmaceutical manufacturers and formulation partners worldwide. Below is a brief overview of the molecule and its commercial relevance.
Etomidate (CAS No. 33125-97-2) is a short-acting intravenous general anesthetic belonging to the imidazole class. It is primarily used for induction of general anesthesia and procedural sedation. Etomidate enhances inhibitory neurotransmission through positive modulation of the GABA-A receptor and is recognized for producing relatively limited cardiovascular depression compared with many other intravenous anesthetic agents.
For pharmaceutical manufacturers and formulation developers, Etomidate is supplied as a pharmaceutical active ingredient with supporting quality documentation such as COA and MSDS available on request. Current supplier data also identifies Etomidate as an API supplied in USP/BP/EP grades.
Key technical parameters for quality evaluation, regulatory review, and sourcing decisions.
| Parameter | Specification |
|---|---|
| Chemical Name | Ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate |
| CAS Number | 33125-97-2 |
| Synonyms | Etomidate; Amidate; Hypnomidate; (+)-Etomidate |
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.29 g/mol |
| Appearance | White to off-white crystalline powder |
| Identification | By IR and HPLC |
| Assay | 98.0%–102.0% on dried basis, USP |
| Loss on Drying | NMT 0.50% |
| Residue on Ignition | NMT 0.10% |
| Specific Optical Rotation | 67.0°–70.0° at 20°C, calculated on dried basis |
| Etomidate Acid | NMT 0.10% |
| Metomidate | NMT 0.10% |
| Any Unspecified Impurity | NMT 0.10% |
| Total Impurities | NMT 1.0% |
| Storage | Store in a cool, dry place and protect from light |
Recommended packing and storage guidance to help maintain product integrity during export and warehousing.
| Parameter | Details |
|---|---|
| Packaging | Available in suitable pharmaceutical-grade packaging according to customer requirements and applicable transportation regulations. |
| Pack Size | To be confirmed based on customer requirements and current manufacturer specification. |
| Container | Properly sealed, labelled and suitable for pharmaceutical API storage and transportation. |
| Storage | Keep tightly closed and store according to the conditions specified in the approved product documentation / SDS. |
| Bulk Packaging | Bulk quantities can be arranged subject to availability and applicable packaging requirements. |
| Shelf Life | As specified by the manufacturer and supported by the applicable product documentation. |
Our team supports commercial inquiries, regulatory grade confirmation, COA/MSDS, and export documentation for pharmaceutical partners worldwide.