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High-quality (R)-1-[1-(4-Chlorophenyl)phenylmethyl]piperazine supplied by Macroline Health Care — a trusted exporter of Pharmaceutical APIs and Advance Intermediates with regulatory grade and documentation support.
Macroline Health Care supplies (R)-1-[1-(4-Chlorophenyl)phenylmethyl]piperazine for pharmaceutical manufacturers and formulation partners worldwide. Below is a brief overview of the molecule and its commercial relevance.
(R)-1-[1-(4-Chlorophenyl)phenylmethyl]piperazine (CAS No. 130018-88-1) is a chiral pharmaceutical intermediate supplied by Macroline Health Care for pharmaceutical and fine-chemical manufacturing applications.
This R-isomer of chlorobenzhydryl piperazine is used as an important intermediate in the synthesis of Levocetirizine and related antihistamine compounds. Its defined stereochemical configuration makes it particularly relevant to processes requiring a chiral pharmaceutical intermediate.
Key technical parameters for quality evaluation, regulatory review, and sourcing decisions.
| Parameter | Specification |
|---|---|
| Chemical Name | (R)-1-[1-(4-Chlorophenyl)phenylmethyl]piperazine |
| CAS Number | 130018-88-1 |
| Synonyms | (R)-1-(p-Chlorobenzhydryl)piperazine; (-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine |
| Molecular Formula | C17H19ClN2 |
| Molecular Weight | 286.80 g/mol |
| Appearance | White solid |
| Melting Point | 91–93°C (literature) |
| Boiling Point | 409.1°C (predicted) |
| Density | 1.158 (predicted) |
| Solubility | Slightly soluble in chloroform, dichloromethane and methanol; slightly soluble in water |
| Category | Pharmaceutical Intermediate |
| Application | Levocetirizine Intermediate |
| Storage | Store tightly closed in a cool, dry and dark place |
| COA | Available |
| MSDS | Available |
Recommended packing and storage guidance to help maintain product integrity during export and warehousing.
| Parameter | Details |
|---|---|
| Packaging | Available in suitable pharmaceutical-grade packaging according to customer requirements and applicable transportation regulations. |
| Pack Size | To be confirmed based on customer requirements and current manufacturer specification. |
| Container | Properly sealed, labelled and suitable for pharmaceutical API storage and transportation. |
| Storage | Keep tightly closed and store according to the conditions specified in the approved product documentation / SDS. |
| Bulk Packaging | Bulk quantities can be arranged subject to availability and applicable packaging requirements. |
| Shelf Life | As specified by the manufacturer and supported by the applicable product documentation. |
Our team supports commercial inquiries, regulatory grade confirmation, COA/MSDS, and export documentation for pharmaceutical partners worldwide.